ZA752296B - Pyrazolobenzazepines - Google Patents
PyrazolobenzazepinesInfo
- Publication number
- ZA752296B ZA752296B ZA00752296A ZA752296A ZA752296B ZA 752296 B ZA752296 B ZA 752296B ZA 00752296 A ZA00752296 A ZA 00752296A ZA 752296 A ZA752296 A ZA 752296A ZA 752296 B ZA752296 B ZA 752296B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrazolobenzazepines
- Prior art date
Links
- VHAPJBVXIABIRJ-UHFFFAOYSA-N pyrazolo[3,4-i][1]benzazepine Chemical class C1=CC=NC2=C3C=NN=C3C=CC2=C1 VHAPJBVXIABIRJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/16—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/475,474 US3947585A (en) | 1974-06-03 | 1974-06-03 | Pyrazolobenzazepines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA752296B true ZA752296B (en) | 1976-03-31 |
Family
ID=23887726
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00752296A ZA752296B (en) | 1974-06-03 | 1975-04-10 | Pyrazolobenzazepines |
| ZA00753555A ZA753555B (en) | 1974-06-03 | 1975-06-02 | Pyrazolobenzazepines, process for their manufacture and pharmaceutical preparations containing them |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00753555A ZA753555B (en) | 1974-06-03 | 1975-06-02 | Pyrazolobenzazepines, process for their manufacture and pharmaceutical preparations containing them |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3947585A (en]) |
| JP (1) | JPS516995A (en]) |
| AU (1) | AU8176175A (en]) |
| BE (1) | BE829779A (en]) |
| DE (3) | DE2524048A1 (en]) |
| DK (1) | DK237075A (en]) |
| FI (1) | FI751622A7 (en]) |
| FR (3) | FR2272662A1 (en]) |
| IL (1) | IL47404A0 (en]) |
| NO (1) | NO751845L (en]) |
| SE (1) | SE7505899L (en]) |
| ZA (2) | ZA752296B (en]) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5461463U (en]) * | 1977-10-07 | 1979-04-28 | ||
| JPS54180099U (en]) * | 1978-06-05 | 1979-12-19 | ||
| NZ192803A (en) * | 1979-02-07 | 1984-08-24 | Hoffmann La Roche | Pyrimido-2-benzazepines and pharmaceutical compositions |
| US4243589A (en) * | 1979-11-30 | 1981-01-06 | Hoffmann-La Roche Inc. | Triazolobenzazepines and processes for their production |
| US4354973A (en) * | 1980-08-05 | 1982-10-19 | Hoffmann-La Roche Inc. | Pyrrolo[3,4-d][2]benzazepines |
| DK347781A (da) * | 1980-08-05 | 1982-02-06 | Hoffmann La Roche | Fremgangsmaade til fremstilling af pyrimido-(4,5-d) (2)-benzezepiner eller farmaceutisk acceptable salte deraf |
| US4379765A (en) * | 1980-08-05 | 1983-04-12 | Hoffmann-La Roche Inc. | Pyrazolobenzazepines |
| US4405518A (en) * | 1981-07-23 | 1983-09-20 | Hoffmann-La Roche Inc. | Pyrrolo[3,4-d] [2] benzazepines |
| US4436662A (en) | 1982-06-28 | 1984-03-13 | Hoffmann-La Roche Inc. | Pyrrolo[3,4-d][2]benzazepinones |
| ES2391577T3 (es) | 2004-05-14 | 2012-11-27 | Millennium Pharmaceuticals, Inc. | Los compuestos y métodos para inhibir la progresión mitótica mediante la inhibición de la aurora quinasa |
-
1974
- 1974-06-03 US US05/475,474 patent/US3947585A/en not_active Expired - Lifetime
-
1975
- 1975-04-10 ZA ZA00752296A patent/ZA752296B/xx unknown
- 1975-05-23 SE SE7505899A patent/SE7505899L/xx unknown
- 1975-05-23 NO NO751845A patent/NO751845L/no unknown
- 1975-05-28 DK DK237075A patent/DK237075A/da unknown
- 1975-05-30 DE DE19752524048 patent/DE2524048A1/de active Pending
- 1975-05-30 DE DE19752543383 patent/DE2543383A1/de active Pending
- 1975-05-30 DE DE19752543382 patent/DE2543382A1/de active Pending
- 1975-06-02 AU AU81761/75A patent/AU8176175A/en not_active Expired
- 1975-06-02 ZA ZA00753555A patent/ZA753555B/xx unknown
- 1975-06-02 IL IL47404A patent/IL47404A0/xx unknown
- 1975-06-02 BE BE156949A patent/BE829779A/xx unknown
- 1975-06-02 FR FR7517130A patent/FR2272662A1/fr not_active Withdrawn
- 1975-06-02 FI FI751622A patent/FI751622A7/fi not_active Application Discontinuation
- 1975-06-03 JP JP50066138A patent/JPS516995A/ja active Pending
-
1976
- 1976-01-09 FR FR7600447A patent/FR2289200A1/fr not_active Withdrawn
- 1976-01-09 FR FR7600446A patent/FR2289187A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU8176175A (en) | 1976-12-09 |
| DE2524048A1 (de) | 1976-01-15 |
| DE2543383A1 (de) | 1976-01-29 |
| SE7505899L (sv) | 1975-12-04 |
| FR2272662A1 (en]) | 1975-12-26 |
| JPS516995A (en]) | 1976-01-20 |
| ZA753555B (en) | 1976-04-28 |
| FR2289200A1 (fr) | 1976-05-28 |
| US3947585A (en) | 1976-03-30 |
| FI751622A7 (en]) | 1975-12-04 |
| DE2543382A1 (de) | 1976-01-29 |
| FR2289187A1 (fr) | 1976-05-28 |
| NO751845L (en]) | 1975-12-04 |
| DK237075A (da) | 1975-12-04 |
| IL47404A0 (en) | 1975-08-31 |
| BE829779A (fr) | 1975-12-02 |
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